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Pyrazinamide is available in tablet form in strengths of 500mg, 750mg, 1000mg and 1200mg respectively. The average dosage recommended for generic Pyrazinamide is 1 tablet daily which must preferably be taken at the same time each day either with or without food and swallowed with a full glass of water. However, if a larger dose has been prescribed by your health care professional you must take Pyrazinamide not more than twice a week unless your health care professional has advised your otherwise.

Furthermore, you must be sure to follow the directions on the prescription label carefully and ask your health care professional or pharmacist to explain any part of Pyrazinamide you do not understand. You must also be sure to take generic Pyrazinamide exactly as directed and refrain from taking a greater or lesser quantity of this medication or altogether taking this medication more or less often than prescribed by your health care professional. Be sure that you do not suddenly discontinue Pyrazinamide without prior confirmation from your health care professional. Your dose must be gradually decreased, since certain conditions may worsen when generic Pyrazinamide is abruptly discontinued. Speak with your health care professional pertaining to the use of Pyrazinamide in the case of children.

While on an ongoing course of generic Pyrazinamide if you notice any of the symptoms listed below or any other symptoms which may seem severe or persistent, you must contact your health care professional.

• Sometimes, generic Pyrazinamide may cause the patient to experience numbness, a tingling of the hands or feet, myalgia, fever, hives, acne and swelling of the face, lips or tongue.

• Furthermore, Pyrazinamide may cause the patient to experience a loss of appetite, nausea, disorientation, vomiting, abdominal pain, fatigue and marginal joint pain.

• Lastly, generic Pyrazinamide may cause the patient to experience skin rashes, an itching sensation, chills, a sore throat, headaches, marginal swelling of the joints and dizziness.

If you are on an ongoing course of generic Pyrazinamide, before you commence taking any new medication (either prescription or OTC), you must first consult your health care professional or pharmacist.

Furthermore, you must be sure to inform your health care professional if you are allergic to generic Pyrazinamide or any other medication in any other form. Your health care professional must also be informed if you are taking any other medication in any other form, including nutritional supplements or herbal products whilst on an ongoing course of this medication.

• Sometimes, Pyrazinamide interacts with various medications, such as Furazolidone, Linezolid, Digoxin, Moclobemide, Phenelzine and Warfarin.

• Furthermore, generic Pyrazinamide interacts with various medications, such as Procarbazine, Selegiline, Isocarboxazid, Quinidine and Tranylcypromine.

• Lastly, Pyrazinamide interacts with various medications, such as Allopurinol, Colchicine, Rifampin, Probenecid and Sulfinpyrazone.

Your health care professional may order certain laboratory and/or medical tests to be performed, such as blood pressure levels, smooth functioning of the kidneys, PAP tests, breast and pelvic tests, a mammogram, blood electrolyte levels and blood cholesterol levels to check your response to Pyrazinamide, monitor your progress and check for side effects. You must be sure to keep all appointments with your health care professional and the laboratory. Do not let anyone else take your prescribed dosage of generic Pyrazinamide and ask your health care professional or pharmacist any questions you have about refilling your prescription.

Furthermore, while on an ongoing course of Pyrazinamide, if you need to undergo any kind of surgery including dental surgery, you must consult your health care professional. If you conceive whilst on a course of generic Pyrazinamide inform your health care professional. You must be sure to inform your health care professional if you are pregnant or breast feeding or planning to conceive. Pyrazinamide passes into breast milk.

Lastly, avoid consuming alcohol and beverages containing even a small percentage of alcohol whilst on an ongoing course of generic Pyrazinamide. It is important that you do not discontinue this medication without first consulting your health care professional. While on an ongoing course of Pyrazinamide, you must also refrain from driving a car or operating any kind of machinery until you know how this medication affects you.

Store Pyrazinamide in the container it came in, keep the lid tightly closed and out of reach of children. Store it at room temperature (between 59 – 86 degrees F or 15 – 30 degrees C) and away from excess heat and moisture.

Furthermore, you must be sure to throw away any generic Pyrazinamide medication that has gotten outdated or is no longer required. But, speak with your pharmacist or health care professional or consult your local waste disposal company about the proper method by which you can safely and effectively discard your unused Pyrazinamide medication.

• It is very important for the patient to know that before consuming Pyrazinamide they must inform their health care professional if they have ever had a history of or are currently suffering from kidney complications, gout, diabetes mellitus or liver complications.

• Furthermore, while on an ongoing course of generic Pyrazinamide you must be sure to stay indoors or wear protective clothing outdoors and use an effective sunscreen lotion if you are required to step outside. You must also make it a point to avoid sun lamps and sun tanning beds or booths. Refrain from smoking since this will only aggravate your current situation.

• Lastly, while on an ongoing course of Pyrazinamide, speak with your health care professional as there are chances of you getting false positive results for tests that check sugar levels in your urine.
If you are diabetic note that pyrazinamide can interfere with urine ketone determination tests, such as Acetest® and Ketostix®. Check with your prescriber or health care professional before you change your diet or the dose of your diabetic medicine. Also, you may speak with your health care professional pertaining to any queries.