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Protopic generic Tacrolimus (topical) Ointment is available in ointment form in a 10gm tube. A thin layer of this medication must be applied twice daily, to skin which must be absolutely dry. If your hands are not part of the area requiring treatment then wash them thoroughly after applying generic Tacrolimus (topical) Ointment. Furthermore, adults may use either Protopic generic Tacrolimus (topical) Ointment 0.1% or 0.03% and children aged 2 years to 15 years must only be applied generic Tacrolimus (topical) 0.03%. Lastly, you must be sure to follow the directions on the prescription label carefully and ask your health care professional or pharmacist to explain any part of generic Tacrolimus (topical) Ointment you do not understand. You must also be sure to apply Protopic generic Tacrolimus (topical) Ointment exactly as directed and refrain from applying a greater or lesser quantity of this medication or altogether applying this medication more or less often than prescribed by your health care professional. Be sure that you do not suddenly discontinue generic Tacrolimus (topical) Ointment without prior confirmation from your health care professional. Your application dose must be gradually decreased, since certain conditions may worsen when Protopic generic Tacrolimus (topical) Ointment is abruptly discontinued. Keep in mind that generic Tacrolimus (topical) should not be applied to children less than 2 years of age and is available only with a prescription provided by your health care professional.

While on an ongoing course of Protopic generic Tacrolimus (topical) Ointment if you notice any of the symptoms listed below or any other symptoms which may seem severe or persistent, you must contact your health care professional. • Sometimes, generic Tacrolimus (topical) Ointment may cause the patient to experience flushing of the skin, an increased sensitivity to hot and cold temperature, acne, nausea, an itching sensation, watery eyes, swollen glands and a burning sensation. • Furthermore, Protopic generic Tacrolimus (topical) ointment may cause the patient to experience warts, muscle pain, an upset stomach, dizziness, swollen hair follicles, a change in skin appearance, skin rashes and headaches.

If you are on an ongoing course of Protopic generic Tacrolimus (topical) Ointment, before you commence taking any new medication (either prescription or OTC), you must first consult your health care professional or pharmacist. Furthermore, you must be sure to inform your health care professional if you are allergic to generic Tacrolimus (topical) Ointment or any other medication in any other form. Your health care professional must also be informed if you are taking any other medication in any other form, including nutritional supplements, preservatives, food dyes, iron supplements or herbal products whilst on an ongoing course of this medication. • Sometimes, Protopic generic Tacrolimus (topical) interacts with various medications, such as Carbamazepine, Itraconazole, Rifabutin, Diltiazem, Colchicine, Indomethacin and Phenytoin. • Furthermore, generic Tacrolimus (topical) interacts with various medications, such as Verapamil, Cyclosporine, Ibuprofen, Rifampin, St. John’s Wart and Ziprasidone.

Do not let anyone else apply your prescribed dosage of Protopic generic Tacrolimus (topical) Ointment and ask your health care professional or pharmacist any questions you have about refilling your prescription. If you conceive whilst on a course of generic Tacrolimus (topical) Ointment inform your health care professional. You must be sure to inform your health care professional if you are pregnant, breast feeding or planning to conceive. You must be aware that Protopic generic Tacrolimus (topical) Ointment passes into breast milk. Furthermore, avoid consuming alcohol and beverages containing even a small percentage of alcohol whilst on an ongoing application course of generic Tacrolimus (topical) Ointment. It is important that you do not discontinue this medication without first consulting your health care professional. While on an ongoing course of Protopic generic Tacrolimus (topical) Ointment, you must also refrain from driving a car or operating any kind of machinery until you know how this medication affects you.

Store Protopic generic Tacrolimus (topical) Ointment in the container it came in, keep the lid tightly closed and out of reach of children. Store it at room temperature (between 59 – 86 degrees F or 15 – 30 degrees C) and away from excess heat and moisture. Furthermore, you must be sure to throw away any generic Tacrolimus (topical) Ointment medication that has gotten outdated or is no longer required. But, speak with your pharmacist or health care professional or consult your local waste disposal company about the proper method by which you can safely and effectively discard your unused Protopic generic Tacrolimus (topical) Ointment.

• It is very important for the patient to know that before applying Protopic generic Tacrolimus (topical) Ointment they must inform their health care professional if they have ever had a history of or are currently suffering from an immunocompromised (weakened) immune system, Herpes simplex (skin blisters), Chickenpox, Netherton’s syndrome, Varicella zoster (shingles), cancer of the lymph system or kidney complications. • Furthermore, while on an ongoing course of generic Tacrolimus (topical) Ointment be sure to stay indoors (away from sunlight) almost all of the time (whether you have applied the medication or not) and away from any harsh artificial light, such as sunlamps or tanning booths. While on an application course of generic Tacrolimus (topical) Ointment make it a point to wear loose clothing and a sun block with minimum SPF15 to protect your skin. • If you suffer from an infection on the area that requires to be treated do not apply Protopic generic Tacrolimus (topical) Ointment. Keep in mind that the area of skin that is being treated by generic Tacrolimus (topical) Ointment must not be covered with bandages, dressings or wraps. • Lastly, you must also make it a point to consult your health care professional if even after applying Protopic generic Tacrolimus (topical) Ointment for 6 full weeks, there has been no improvement.